Search results for: light sheet

A Light Sheet Microscope Project Description :

Iowa State University requests proposals to provide a light sheet microscope system for the High Resolution Microscopy Facility of the Office of Biotechnology. The microscope system will be utilized by numerous researchers from across the ISU campus. Systems offered must meet the minimum specifications stated herein. Demonstration of offered system and sample analysis is REQUIRED.

Iowa State University requests proposals to provide a light sheet microscope system for the High Resolution Microscopy Facility of the Office of Biotechnology. The microscope system will be utilized by numerous researchers from across the ISU campus. Systems offered must meet the minimum specifications stated herein. Demonstration of offered system and sample analysis is REQUIRED.

The current focus of the Lab is to elucidate the basic cellular and molecular mechanisms underlying experience-dependent regulation of frontal cortical circuits in model organisms.Purpose and Objectives:The lab needs the ALPHA3 light sheet system addition to their existing Olympus microscope for rapidly imaging whole mouse brains. Light sheet imaging allows for rapid and efficient imaging of whole brains or thick sections.

sheet imaging including 1X, 4X and 12X with zoom magnifications from 1X-30X range, large working distance up to 16 mm, and a large field of view up to 33 mm diagonalg)    optimized light sheet optics including adjustable light sheet NA and width for high-resolution, high-quality deep cleared tissue imaging at subcellular resolution with minimal illumination, photobleaching and spectral bleedthrough artifactsh)    compatibility with specimen imaging

The MBF Clear Scope light-sheet theta microscope is a highly specialized microscope capable of scanning large tissue specimens measuring up to 6 x 4 inches. The system's geometry allows any large section of cleared tissue up to 12 mm thick to be scanned using up to 7-different wavelengths of light. The light sheet theta microscope is a patented light-sheet geometry and not available from any other vendor.

This is accomplished through biochemical clearing of the tissue and use of a light sheet microscope.Purpose and Objectives:The National Institute of Mental (NIMH), Systems Neuroscience Imaging Resource (SNIR) requires an upgrade of the existing LaVision light sheet microscope system to ensure it better meets the needs of users by acquiring high quality images.