Search results for: screening library of small

THIS IS NOT A REQUEST FOR QUOTE/PROPOSALS.On September 8, 2021; in response to the requirements of Solicitation 75N95021Q00326, the National Institute on Drug Abuse (NIDA) awarded a Purchase Order No. 75N95021P00508 to MedChemExpress, LLC for the Compound library of 197 bioactive compounds. The estimated Period of Performance is from September 16, 2021 to January 16, 2022. An award shall be made on a Firm Fixed Price basis.

Salient characteristics:- Small molecules must have validated biological and pharmacological activities.- Must be available for high-throughput screening (HTS) and high-content screening (HCS).- Must come with detailed biological and chemical information with LC/MS and NMR reports to ensure high quality.7.    

NON-COMPETITIVECOMBINED SYNOPSIS / SOLICITATIONTitle: Acquisition of 11,000 Small Molecules for NCATS Screening Library(i) This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued.

on screening against small molecule of the library.

However, screening may be conducted on small libraries of synthetic or natural product compounds of unknown activity and on hit or lead compounds generated through NIH-funded HTS or chemistry programs.  Compounds will be provided by the research community, primarily NIH-supported investigators. 

of 3,750 small molecules for the Genesis screening library.

A fluid handler that is able to dispense small amounts of chemical and nucleic acid screening libraries rapidly from source plates without the need for costly disposable pipette tips is required. A tip less system would drastically reduce reagent wastage due to pipetting error and droplets clinging to tips, extending the number of experiments that can be executed from various libraries.