PREVENT Cancer Preclinical Drug Development Program: Toxicology and Pharmacology Testing-CANCELLATION

Added:
Nov 27, 2017 12:16 pm Notice of Intent to Sole Source
PREVENT Cancer Preclinical Drug Development Program:
Toxicology and Pharmacology Testing
This is a sole source synopsis for the I ndefinite Delivery Indefinite Quantity
(IDIQ) contracts within the PREVENT Cancer Preclinical Drug Development
Program: Toxicology and Pharmacology Testing. This announcement
constitutes the only synopsis for this requirement, is issued for notification
purposes only and is not a request for competitive proposals.
The National Cancer Institute (NCI) plans to issue modifications to increase
the ceilings on each contract in the IDIQ Toxicology pool to provide continued
support in the conduct of toxicological and pharmacological evaluations of
potential cancer preventive agents for Investigational New Drug applications
to the Food and Drug Administration (FDA) for phase 0, 1-3 clinical studies.
This work is accomplished through studies in genotoxicity

testing, general
toxicology in experimental animals, reproductive toxicology studies in rodents
and rabbits and other specialized studies. The modifications for this
requirement are anticipated to take place on or about September 30, 2017.
The five contractors currently within the Toxicology IDIQ pool are as follows:
HHSN261201500021I, SRI International, 333 Ravenswood Ave., Menlo Park,
CA 94025
HHSN261201500022I, Southern Research Institute, 2000 9th Ave. S.,
Birmingham, AL 35205
HHSN261201500023I, Lovelace Biomedical & Environmental Research
Institute, 2425 Ridgecrest Dr. SE, Albuquerque, NM 87108
HHSN261201500024I, IIT Research Institute, 10 W. 35th Street, Chicago, IL
60616
HHSN261201500026I, University of Illinois at Chicago, 506 S. Wright St. 364
Henry Admin Bldg, Urbana, IL 61801
These modifications will increase the ceiling value on the Base IDIQ
contracts from $9 million by $10 million to $19 million. In order to ensure
operation and continuity of essential research and development services
during the next two cycles of the PREVENT Program, NCI needs to increase
the ceiling, which will allow for the funding of complex task orders that include
immunoprevention projects associated with specialized, expensive assays
and procedures, among other projects. The NCI intends to issue these
modifications on a non-competitive basis to each of the five contractors in the
Tox IDIQ pool in accordance with 10 U.S.C 2304(c)(1), as implemented by
FAR 6.302-1(a)(2), "Only one responsible source and no other supplies or
services will satisfy agency requirements."
This notice is not a request for competitive proposals; however, if any
interested and responsible source, especially small businesses, believes it
can meet the requirements, submit a capability statement, proposal, or
quotation, which shall be considered by the agency. The statement of
capabilities and any other information furnished must be in writing and must
contain material in sufficient detail to allow NCI to determine if the party can
perform the requirement. Interested organizations may submit their
capabilities and qualifications to perform the effort in writing to the identified
point of contact not later than 3:30 p.m., Eastern Standard Time, on August
29, 2017. Such capabilities/qualifications will be evaluated solely for the
purpose of determining whether or not to conduct this procurement on a
competitive basis. A determination by the Government not to compete this
proposed contract action based upon responses to this notice is solely within
the discretion of the Government. Oral and facsimile communications shall
not be accepted in response to this notice.
In accordance with FAR 16.505(b)(8), the following individual has been
designated as the NIH Ombudsman for these task order contracts:
Dr. Sherry Mills
NIH Competitio n Advocate for R&D Contracts
6705 Rockledge Drive, Suite 305
Bethesda, MD 20892
Phone: 301-435-2729
E-mail: sherry.mills@nih.gov
DISCLAIMER: THIS NOTICE IS FOR INFORMATIONAL AND PLANNING
PURPOSES ONLY. THIS IS NOT A REQUEST FOR QUOTE AND IS NOT A
COMMITMENT BY THE US GOVERNMENT TO PROCURE SUBJECT
PRODUCTS. NO SOLICITATION SHALL RESULT FROM THIS NOTICE. NO
FUNDS ARE AVAILABLE TO ACCOUNT FOR PREPARATION OF
RESPONSES TO THIS NOTIFICATION. THE GOVERNMENT WILL USE
THE INFORMATION RECEIVED TO DETERMINE WHETHER OTHER
SOURCES ARE AVAILABLE THAT ARE CAPABLE TO SATISFY THIS
REQUIREMENT.

Added:
Nov 29, 2017 12:02 pm This is being cancelled and will be re-posted at a later date.