TCS SP8 STED 3X Microscope Upgrades for the National Institute of Neurological Disorders and Stroke(NINDS) Synaptic Transmission Section

TCS SP8 STED 3X Microscope Upgrades for the National Institute of Neurological Disorders and Stroke(NINDS) Synaptic Transmission Section(Expired)

Dates

Bid Notification started - 10 Sep, 2017 (14 months ago) - TCS SP8 STED 3X Microscope Upgrades for the National Institute of Neurological Disorders and Stroke(NINDS) Synaptic Transmission Section

Start Date

10 Sep, 2017 (14 months ago)
Bid Notification due - 10 Sep, 2017 (14 months ago) - TCS SP8 STED 3X Microscope Upgrades for the National Institute of Neurological Disorders and Stroke(NINDS) Synaptic Transmission Section

Due Date

18 Sep, 2017 (14 months ago)
Bid Notification - TCS SP8 STED 3X Microscope Upgrades for the National Institute of Neurological Disorders and Stroke(NINDS) Synaptic Transmission Section

Opportunity Type

Bid Notification
HHS-NIH-NIDA-SSSA-NOI-17-695 - TCS SP8 STED 3X Microscope Upgrades for the National Institute of Neurological Disorders and Stroke(NINDS) Synaptic Transmission Section

Opportunity Identifier

HHS-NIH-NIDA-SSSA-NOI-17-695
Bid Notification Department of Health and Human Services - TCS SP8 STED 3X Microscope Upgrades for the National Institute of Neurological Disorders and Stroke(NINDS) Synaptic Transmission Section

Customer / Agency

Department of Health and Human Services
Bid Notification 6001 Executive Boulevard Room 4211, MSC 9559 Bethesda, Maryland 20892-9559 United States - TCS SP8 STED 3X Microscope Upgrades for the National Institute of Neurological Disorders and Stroke(NINDS) Synaptic Transmission Section

Location

6001 Executive Boulevard Room 4211, MSC 9559 Bethesda, Maryland 20892-9559 United States
From: Federal Government(Federal)
Added: Sep 10, 2017 1:48 pm TCS SP8 STED 3X Microscope Upgrades for the National Institute of Neurological Disorders and Stroke(NINDS) Synaptic Transmission Section Pre-Solicitation Notice of Intent to Sole Source HHS-NIH-NIDA-SSSA-NOI-17-695 INTRODUCTIONThis is a combined synopsis/pre-solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. This acquisition is being conducted in accordance with the procedures of FAR Part 13--Simplified Acquisition Procedures and FAR Part 12--Acquisition of Commercial Items. The solicitation number is HHS-NIH-NIDA-SSSA-NOI-17-695 and the solicitation is issued as a PRE-SOLICITATION, NOTICE OF INTENT, to award a contract on a noncompetitive basis to Leica Microsystems Inc located at 1700 Leider Lane, Buffalo Grove, IL 60061. REGULATORY & STATUTORY AUTHORITYThis acquisition is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13--Simplified Acquisition Procedures, Subpart 13.106-1, only one responsible source and no other supplies or services will satisfy agency requirements, and FAR Part 12--Acquisition of Commercial Items and is NOT expected to exceed the simplified acquisition threshold. Contracts awarded using FAR Part 13--Simplified Acquisition Procedures are exempt from the requirements of FAR Part 6--Competition Requirements. The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2005-95, dated January 19, 2017. NORTH AMERICAN INDUSTRY CLASSIFICATION SYSTEM (NAICS) CODEThe associated NAICS code for this requirement is 334516 with size standard of 1,000 Employees. CONTRACTING WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION (INCLUDING BRAND-NAME) DETERMINATIONThe non-competitive determination is based upon the market research conducted as prescribed in FAR Part 10--Market Research, which indicates that only Leica Microsystems Inc is capable of providing the necessary support services. Specifically, Leica Microsystems Inc is the original equipment manufacturer (OEM) of the instruments requiring service and the instruments are proprietary to this company. As such, only Leica Microsystems Inc is authorized to provide service and parts for this equipment. Use of any other contractor would place equipment integrity in jeopardy which would then risk continuity of science; should the equipment not remain fully operational to original equipment manufacturer standards, standardization of longitudinal research study data would be jeopardized and any loss of this data would be to the serious detriment of the Neurological Disorders and Stroke (NINDS) mission. Accordingly, only Leica Microsystems Inc is capable of providing the required support services. This synopsis is not a request for competitive proposals. However, interested parties may identify their interest and capability to respond to this notice. A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement. DESCRIPTION OF REQUIREMENT BackgroundThe National Institute of Neurological Disorders and Stroke (NINDS) Synaptic Transmission Section (STS) combines news technique of microscopy and cell biological approaches to investigate the fundamental process of exocytosis and endocytosis as well as how the fusion pore opens, expands and close. Fluorescence microscopy is a fundamental technique used in the laboratory and the FLIM module upgrade is required to study the molecular mechanism of the fusion pore opening and closure. The 775 STED laser is required to improve the visualization of proteins involved in the exocytosis and endocytosis process without serious photobleaching or phototoxicity during super-resolution imaging. Purpose and ObjectivesThe purpose of this acquisition is to procure microscope upgrades for an existing an Leica TCS SP8 STED 3 X Microscope. A Fluorescence Lifetime Imaging Microscopy (FLIM) module and 775 STED laser upgrade are required to monitor, image and visualize protein interaction in living cells. This requirement is issued on a sole-source basis. Project Description Purchase Description: Trade name: N/A Product's brand name: FLIM Microscope module, STED 775 laser upgrade Manufacturer's name: Leica Model, type, catalog, and/or part number(s): 158001500, 158005434, 158005421, 156502140, 158001502, 158005231, 158004511, 158004760, 158005652 Salient characteristics Contractor shall provide the NINDS STS one (1) FLIM Module [Leica Item #: 158001500, 158005434, 158005421, 156502140, 158001502, 158005231, 158004511, 158004760, 158009103, 158009120] and one (1) STED 775 laser upgrade [Leica Item #: 158005652] that meets shall meet the following requirements: Leica Part Number Item Name Description 158001500 External Chiller Air-cooled heat exchanger 158005434 SMD Software Package FLIM 64 bit Software for acquisition of FLIM data 158005421 Electronic and detector package 1 SP Hybrid Detector for SMD data acquisition with high time resolution 156502140 Pulse picker upgrade for White Light Laser generation 2 It allows to select the white light laser repetition rate 158001502 SP module cooling Circuit for external cooling of the spectral module. The heat removal reduces dark noise of spectral hybrid detector leading to maximum signal-noise ratio 158005231 SMD excitation like White Light Laser Package needed to generate a synchronization signal from white light laser. The synchronization signal is a prerequisite for lifetime based measurement like FLIM 158004511 notch filter set Positioned in the fluorescence detection axis. It provides additional suppression of excitation light 158004760 Trigger Unit For communication between SP scan head and external. Additionally, it is used for synchronization of confocal imaging controlled by LASAF and FLIM imaging by FLIM specific software. 158009103 405 nm laser coupler Optical and mechanical coupling interface for laser with pulsed 405nm for FLIM 158009120 DMOD 405nm laser upgrade Continuous wave laser with wavelength 405nm for fluorescence imaging with dyes. Laser intensity is directly modulated, suitable for imaging with region of interest. 158005652 STED 775 laser upgrade Laser with emission wavelength at 775 nm, output power superior at 1.5W. The mode of operation is pulsed (80MHz) with externally triggered. QuantityOne (1) FLIM microscope module One (1) STED 775 laser upgrade Delivery DateContractor shall delivery within six (6) weeks after receipt of order. Installation and training shall occur within four (4) weeks of delivery. Training shall be one (1) day and on-site. Contractor shall provide an original equipment manufacturer (OEM) certified service technician to perform installation and training. Delivery, installation and training must be performed at 35 Convent Drive, Room 2B912, Bethesda, MD 20892 between the hours of 8:00 am and 5:00 pm, local prevailing time, Monday through Friday. Period of PerformanceContractor shall provide a one (1) year warranty that covers defects in manufacturing and excludes wear and consumable items. Installation and system-use training shall also be provided. Installation and training must be provided by a manufacturer certified service technician Government ResponsibilitiesNINDS will provide access to the facilities located at 9800 Medical Center Drive, Building B, Bethesda, MD 20850 as necessary. Reporting RequirementsThere are no reporting requirements Non-Personal Service StatementIn accordance with FAR 37.104, this requirement is for non-personal services and does not include any inherently governmental functions; functions that are closely associated with inherently governmental functions; unauthorized personal services; critical and/or core functions. Place of Performance The place of performance shall be the National Institute of Neurological Disorders and Stroke site located at 35 Convent Drive, Room 2B912, Bethesda, MD 20892. Contract TypeA Firm Fixed Price Purchase Order is contemplated. The order shall be sourced via the Open Market on a single-source basis. RESPONSE INSTRUCTIONSResponses to this solicitation must include sufficient information to establish the interested parties' bona-fide capabilities of providing the product or service. Offerors must provide both 1) a technical response and 2) a separate price quote. The price quote shall include: unit price, list price, shipping and handling costs, delivery days after contract award, delivery terms, prompt payment discount terms, F.O.B. Point (Destination or Origin), product or catalog number(s); product description; and any other information or factors that may be considered in the award decision. Such factors may include: past performance; special features required for effective program performance; trade-in considerations; probable life of the item selected as compared with that of a comparable item; warranty considerations; and maintenance availability. PLEASE ENSURE THAT ALL EVALUATION CRITERIA ARE SPECIFICALLY ADDRESSED IN ANY RESPONSE(S) SUBMITTED. EVALUATION CRITERIAFAR clause 52.212-2, Evaluation - Commercial Items (October 2014) applies to this acquisition and the specific evaluation criteria to be included in paragraph (a) of that provision are as follows: The Government will award a contract resulting from this requirement on the basis of best value, technical factors and price considered. Technical factors together shall be considered more important than price and all technical evaluation factors are detailed below. Factor 1: Supply Capability The contractor shall detail in its technical proposal how it shall meet each of the project requirements. This shall include detailed specifications and capabilities of the offered microscope system upgrades. Technical approach shall be evaluated for the ways in which the proposed microscope system upgrades meets or exceeds the requirement. Exceeding requirements shall be considered favorably. Factor 2: Delivery, Installation and Training The contractor shall detail in its technical proposal how it shall meet the delivery, installation and training requirements. The Government shall evaluate for ability to meet or exceed these requirements. Proposals must include a delivery lead-time as well as installation and training by an original equipment manufacturer (OEM) service technician. Factor 3: Warranty The contractor shall detail in its technical proposal meet the warranty requirement. The Government shall evaluate for ability to meet or exceed these requirements. Factor 4: Past Performance The Contractor shall provide a list of two (2) contracts or purchase orders completed during the past five (5) years, similar in size and scope to the maintenance requirements outlined in this Statement of Work. Experience must be specific to provision of laboratory instrument maintenance and shall include the following information for each contract or purchase order listed: a. Name of Contracting Organization b. Total Contract Value c. Description of Requirement d. Contract Period of Performance Past Performance shall be evaluated for relevance to the current requirement. Technical proposals will be evaluated using a summary adjectival rating in accordance with the following scale: Excellent The proposal has exceptional merit and reflects an excellent approach which will clearly result in the superior attainment of all requirements and objectives. This clearly achievable approach includes several advantageous characteristics of substance, and very few disadvantages, which can be expected to result in outstanding performance. The risk of unsuccessful performance is very low as the proposal provides solutions which are unquestionably feasible and practical. These solutions are further considered very low risk in that they are exceptionally clear and precise, fully supported, and demonstrate a clear understanding of the requirements. Risk Level: Very Low Good The proposal demonstrates a sound approach which is expected to meet all requirements and objectives. This sound approach includes advantageous characteristics of substance, and few relatively minor disadvantages, which collectively can be expected to result in satisfactory performance. The risk of unsuccessful performance is low as the proposal contains solutions which are considered feasible and practical. These solutions are further considered to reflect low risk in that they are clear and precise, supported, and demonstrate an understanding of the requirements. Risk Level: Low Acceptable The proposal demonstrates an approach which is capable of meeting all requirements and objectives. The approach includes both advantageous and disadvantageous characteristics of substance, where the advantages are not outweighed by the disadvantages. Collectively, the advantages and disadvantages are likely to result in acceptable performance. The risk of unsuccessful performance is moderate, as the proposal solutions are generally feasible and practical. These solutions may also be considered to reflect moderate risk in that they may be somewhat clear and precise, partially supported, and/or demonstrate a general understanding of the requirements. Risk Level: Neutral Marginal The proposal demonstrates an approach which may not be capable of meeting all requirements and objectives. The approach has disadvantages of substance and advantages, which if they exist, are outweighed by the disadvantages. Collectively, the advantages and disadvantages present a low or questionable likelihood of resulting in satisfactory performance. The risk of unsuccessful performance is high as the proposal contains solutions which may not be feasible and practical. These solutions may also be considered to reflect high risk in that they lack clarity and precision, are generally unsupported, and/or do not demonstrate a complete understanding of the requirements. Risk Level: High Unacceptable The proposal demonstrates an approach which, based on a very high risk, will very likely not be capable of meeting all requirements and objectives. This approach has several disadvantages of substance, and advantages which, if they exist, are outweighed by disadvantages. Collectively, the advantages and disadvantages are unlikely to result in satisfactory performance. The risk of unsuccessful performance is very high as the proposal contains solutions which are not feasible and practical. The solutions may also be considered to reflect very high risk in that they lack any clarity or precision. Risk Level: Very High APPLICABLE TERMS AND CONDITIONS INCORPORATED BY REFERENCEThe FAR clauses and provisions below shall apply to this solicitation. 1. All Offerors MUST be actively registered in the System for Award Management (SAM) www.sam.gov. 2. The provision at FAR clause 52.212-1, Instructions to Offerors - Commercial Items (JAN 2017), applies to this acquisition. 3. A completed copy of the provision at FAR clause 52.212-3, Offeror Representations and Certifications - Commercial Items (JAN 2017), is required with any offer submitted. This requirement may be met by completion of the provision in the System for Award Management. 4. FAR Clause 52.212-4, Contract Terms and Conditions - Commercial Items (JAN 2017) is applicable to this acquisition. 5. FAR Clause 52.212-5 Contract Terms and Conditions Required to Implement Statutes or Executive Orders - Commercial Items (JAN 2017) apply to this acquisition. The following clauses shall be checked/included in this clause: 52.204-10, Reporting Executive Compensation and First-Tier Subcontract Awards (Oct 2015) 52.209-6, Protecting the Government's Interest When Subcontracting with Contractors Debarred, Suspended, or Proposed for Debarment. (Oct 2015) (31 U.S.C. 6101 note). 52.217-5, Evaluation of Options (July 1990). 52.217-9 Option to Extend the Term of the Contract. (March 2000). 52.219-4, Notice of Price Evaluation Preference for HUBZone Small Business Concerns (OCT 2014) (if the offeror elects to waive the preference, it shall so indicate in its offer) 52.219-28, Post Award Small Business Program Rerepresentation (Jul 2013) 52.222-3, Convict Labor (June 2003) 52.222-19, Child Labor-Cooperation with Authorities and Remedies (Feb 2016) 52.222-21, Prohibition of Segregated Facilities (Apr 2015). 52.222-26, Equal Opportunity (Sept 2016) 52.222-36, Equal Opportunity for Workers with Disabilities (Jul 2014) 52.222-50, Combating Trafficking in Persons (Mar 2015) 52.222-53, Exemption from Application of the Service Contract Labor Standards to Contracts for Certain Services-Requirements (May 2014) 52.223-18, Encouraging Contractor Policies to Ban Text Messaging While Driving (AUG 2011) 52.225-13, Restrictions on Certain Foreign Purchases (June 2008) 52.232-33, Payment by Electronic Funds Transfer-System for Award Management (Jul 2013) 6. The Defense Priorities and Allocations System (DPAS) are not applicable to this requirement. In addition, the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size must be included in the response. CLOSING STATEMENTAll responsible sources may submit a bid, proposal, or quotation which shall be considered by the agency. All responses must be received by the closing date of this announcement must reference solicitation number HHS-NIH-NIDA-SSSA-NOI-17-695. Responses shall be submitted electronically to jermaine.duncan@nih.gov. Fax responses will not be accepted. For information regarding this solicitation, contact Jermaine Duncan by email at jermaine.duncan@nih.gov or by phone at (301) 827-7515.

Location

Country : United States

State : Maryland