Clinical SNP and/or CGH microarray with targeted coverage of neuropsychiatric phenotypes

Document Type:  Combined Synopsis/SolicitationSolicitation Number: RFQ-NIAID-2132374Posted Date: 06/16/2022Response Date: 06/26/2022Set Aside: NoneNAICS Code: 541380, Testing LaboratoriesClassification Code: Q301 Contracting Office Address:Department of Health and Human Services, National Institutes of Health, National Institute of Allergy & Infectious Diseases/AMOB, 903 S 4th Street, Hamilton, MT 59840Title: Clinical SNP and/or CGH microarray with targeted coverage of neuropsychiatric phenotypesPrimary Point of Contact:  Dana Monroe; dana.monroe@nih.govDescription: This notice is a combined synopsis/solicitation for commercial items using Simplified Acquisition Procedures. This acquisition will be made in accordance with the format in Federal Acquisition Regulation (FAR) Subpart 12.6 “Streamlined Procedures for Evaluation and solicitation for commercial Items,” as applicable, and as supplemented with additional information

included in this notice. This announcement constitutes the only solicitation (a written solicitation will not be issued) and quotes are being requested. The Solicitation number is RFQ-NIAID-2132374 and the solicitation is issued as a Request for Quotes (RFQ).This acquisition will be processed under FAR Part 13 Simplified Acquisition Procedures (SAP). The solicitation documents and incorporated provisions and clauses are those in effect through Federal Acquisition Circular (FAC)2022-06 May 26, 2022.The North American Industry Classification System (NAICS) code for this procurement is 541380, Testing Laboratories, with a small business size standard of $15 million. The requirement is being competed full and open competition, un-restricted and without a small business set-aside.The National Institute of Allergy and Infectious Diseases (NIAID) has a requirement for:Clinical SNP and/or CGH microarray with targeted coverage of neuropsychiatric phenotypes, QTY 50 samplesClinical SNP and/or CGH microarray with targeted coverage of neuropsychiatric phenotypes (N = 150)Sample processing and microarray scanning.Feature extraction: Processing of raw image files.CNV calls: Use of the vendor’s genetics pipeline for making copy-number calls from the microarray data.Report: Data review by the vendor’s Genetics team with input from NIAID team for determination of which copy-number calls should be reported clinically. Generation of a report for use by the NIAID team.Web-based access to cases and database: Online access for members of the NIAID team to the vendor database of prior results. This is useful for interpretation and clinical reporting.Data release of raw image files and any intermediate files upon request.NIAID Custom Clinical Chromosomal Microarray Analysis (N = 280)Sample processing and microarray scanning.Feature extraction: Processing of raw image files.CNV calls: Use of the vendor’s genetics pipeline for making copy-number calls from the microarray data.Report: Data review by the vendor’s Genetics team with input from NIAID team for determination of which copy-number calls should be reported clinically. Generation of a report for use by the NIAID team.Web-based access to cases and database: Online access for members of the NIAID team to the vendor database of prior results. This is useful for interpretation and clinical reporting.Data release of raw image files and any intermediate files upon request.The Contractor shall provide plates for shipping and all consumable reagents except those mentioned below. NIAID will supply patient samples. NIAID will also supply microarray chips for the NIAID custom clinical chromosomal microarray analysis.REPORTING REQUIREMENTS AND DELIVERABLESTurn-around time for microarrays is 2 weeks from the time the contractor receives the patient sample.Report: Data review by the vendor’s Genetics team with input from NIAID team for determination of which copy-number calls should be reported clinically. Generation of a report for use by the NIAID team.Web-based access to cases and database: Online access for members of the NIAID team to the vendor database of prior results. This is useful for interpretation and clinical reporting.Data release of raw image files and any intermediate files upon request.Place of Performance: NIH, 9000 Rockville Pike, BLDG 10 Clinical Center, Bethesda, MD 20852, United States.  FOB: DestinationThe government intends to award a firm fixed price purchase order to the responsible contractor as a result of this RFQ that will include the terms and conditions set forth herein.  By submitting a quotation, you are accepting that all government terms and conditions set forth herein shall prevail over the award. The award will be based the lowest price technically acceptable. The Technical evaluation will be based on the following: technical capability to meet the requirements listed on the Bill of Materials, and then price.The following FAR provisions apply to this acquisition: FAR 52.212-1 Instructions to Offerors Commercial Items (NOV 2021)FAR 52.212-3 Offerors Representations and Certifications - Commercial Items (MAY 2022)FAR 52.204-7 System for Award Management (OCT 2018)(Offerors must complete annual representations and certifications on-line at http://www.sam.gov/ in accordance with FAR 52.212-3 Offerors Representations and Certifications- Commercial Items (Please ensure 52.209-2 -- Prohibition on Contracting with Inverted Domestic Corporations--Representation. (Nov 2015) is updated in your SAM record)FAR 52.203-18 Prohibition on Contracting with Entities that Require Certain Internal Confidentiality Agreements – Representation (JAN 2017)52.204–26 Covered Telecommunications Equipment or Services-Representation(OCT 2020) *** Must complete representation if attached to this solicitation- see attachment 52.204-26The following FAR contract clauses apply to this acquisition:FAR 52-212-4 Contract Terms and Conditions Commercial Items (NOV 2021)FAR 52-212.5 Contract Terms and Conditions Required to Implement Statutes or Executive Orders Commercial Items (MAY 2022)*The applicable subparagraphs of FAR52.212-5 are included in the attachment to this posting.FAR 52.232-40 Providing Accelerated Payments to Small Business Subcontractors (NOV 2021)FAR 52.204-13 System for Award Management Maintenance (Oct 2018)FAR 52.204-25 Prohibition on Contracting for Certain Telecommunications and Video Surveillance Services or Equipment (NOV 2021)HHSAR 352.222-70, Contractor Cooperation in Equal Employment Opportunity Investigations (December 2015)52.252-2 -- Clauses Incorporated by Reference. (Feb 1998)This contract incorporates one or more clauses by reference, with the same force and effect as if they were given in full text. Upon request, the Contracting Officer will make their full text available. Also, the full text of a clause may be accessed electronically at this address:  http://farsite.hill.af.mil/vffara.htmBy submission of an offer, the offeror acknowledges the requirement that a prospective awardee shall be registered in the System for Award Management (SAM) database prior to award, during performance, and through final payment of any contract, basic agreement, basic ordering agreement, or blanket purchasing agreement resulting from this solicitation (www.sam.gov).Copies of the above-referenced provisions and clauses are available from http://www.acquisition.gov/far/loadmainre.html & http: //www.hhs.gov/regulation/index.html or, upon request, either by telephone or fax.Submission shall be received not later than June 26, 2022 at 5:00pm EDTOffers may be e-mailed to Dana Monroe at dana.monroe@nih.gov.  Offers shall include RFQ number in the subject line (RFQ-NIAID-2132374). Late submissions shall be treated in accordance with the solicitation provision at FAR 52.212-1(f)All responsible sources may submit an offer that will be considered by this Agency. Any questions or concerns regarding this solicitation should be forwarded in writing via e-mail to Dana Monroe at dana.monroe@nih.gov.