Statement of Need and Purpose: The NIH is seeking executive (senior scientific)-level, industry-experienced drug discovery and development consultants with expertise in Medicinal Chemistry to provide technical guidance in the area of Medicinal Chemistry to the following programs:• Medicinal Chemistry consulting to procure consultant services to provide technical recommendations to the NIH Blueprint Neurotherapeutics Network drug discovery and development programs.• Help End Addiction Long-Term [HEAL] initiative. The HEAL initiative aims to optimize non-addictive therapies [small molecules and biologics] to treat pain.• Other NIH neuroscience-focused drug discovery and development programs.Amendment 1 Attached - Q&A postedAmendment 2 Attached - Q&A